My Jupyter notebooks are not stored on my C drive but the Jupyter UI does not let you select a new drive.
Start a terminal, navigate to the desired location and enter the following command:
Generate a configuration file then uncomment and set the c.NotebookApp.notebook_dir value to the desired location.
To generate the configuration file use the Anaconda prompt and run the following command:
jupyter notebook --generate-config
This will generate a configuration file that can be used to set the default directory.
Open the file in an editor and locate the line for c.NotebookApp.notebook_dir and uncomment the line.
Set the value to the location you want Jupyter to use.
Restart Jupyter and it should default to your new location.
If you use Solution 2 you will lose the ability to have the jupyter notebook command from a command prompt open in the current folder.